Altered pattern of immunohistochemical staining for glial fibrillary acidic protein (GFAP) in the forebrain and cerebellum of the mutant spastic rat.

doi:10.1016/0891-0618(94)00042-r

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Article

Altered pattern of immunohistochemical staining for glial fibrillary acidic protein (GFAP) in the forebrain and cerebellum of the mutant spastic rat.

Journal of chemical neuroanatomy - 1 Mar 1995

Wagemann E, Schmidt-Kastner R, Block F, Sontag K H

Abstract excerpt

The spastic rat is a neurological mutant of the Han-Wistar strain with prominent spasticity, tremor, and ataxia. Neurodegeneration is found in the CA3 sector of the hippocampus and in Purkinje cells of the cerebellum. We examined the forebrain and cerebellum of spastic rats for glial reactions by...

Topics

Animals
Astrocytes
Biomarkers
Brain Chemistry
Cerebellum
Disease Models, Animal
Glial Fibrillary Acidic Protein
Immunohistochemistry
Mutation
Nerve Degeneration
Prosencephalon
Rats
Rats, Mutant Strains
Rats, Wistar
Spasm

Source

Open in PubMed

Identifiers

PMID: 7598815
DOI: 10.1016/0891-0618(94)00042-r

Genes

GFAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7598815-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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