Purkinje cell loss and astrocytosis in the cerebellum in familial and sporadic Alzheimer's disease.

doi:10.1016/0304-3940(96)12875-5

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Article

Purkinje cell loss and astrocytosis in the cerebellum in familial and sporadic Alzheimer's disease.

Neuroscience letters - 16 Aug 1996

Fukutani Y, Cairns N J, Rossor M N, Lantos P L

Abstract excerpt

In order to elucidate further the pathological differences between familial Alzheimer's disease (FAD) and sporadic Alzheimer's disease (SAD), Purkinje cells and astrocytosis in the cerebellum of 10 FAD patients including two cases with the beta-amyloid precursor protein (APP) gene mutation in cod...

Topics

Adult
Aged
Aged, 80 and over
Alzheimer Disease
Amyloid beta-Protein Precursor
Astrocytes
Cadaver
Cell Count
Cell Death
Cerebellum
Humans
Immunohistochemistry
Middle Aged
Mutation
Purkinje Cells

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