Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transcriptional responses of human epidermal keratinocytes to cytokine interleukin‐1

16 Oct 2007

Abstract excerpt

Interleukin-1 is a proinflammatory and immunomodulatory cytokine that plays a crucial role in inflammatory diseases of the skin, including bacterial infections, bullous diseases, UV damage, and especially psoriasis. To characterize the molecular effects of IL-1 in epidermis, we defined the transcriptional changes in human epidermal keratinocytes 1, 4, 24, and 48 h after treatment with IL-1alpha. IL-1...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Immune Response and Inflammation
Share to Antimicrobial Peptides and Activities
Share to Dermatology and Skin Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 17941080
DOI: 10.1002/jcp.21300

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transcriptional responses of human epidermal keratinocytes to cytokine interleukin‐1PMID 17941080Read ↗

Expression of interleukin (IL)-1 family members upon stimulation with IL-17 differs in keratinocytes derived from patients with psoriasis and healthy donorsSemantic proximity Read ↗

Interleukin-1 Induces Transcription of Keratin K6 in Human Epidermal KeratinocytesSemantic proximity Read ↗

The Psoriatic Transcriptome Closely Resembles That Induced by Interleukin-1 in Cultured KeratinocytesSemantic proximity Read ↗

Interleukin-1: A key inflammatory mediator in psoriasis?Semantic proximity Read ↗

Pathway-specific Profiling Identifies the NF-κB-dependent Tumor Necrosis Factor α-regulated Genes in Epidermal KeratinocytesSemantic proximity Read ↗

Inducible deletion of the Blimp-1 gene in adult epidermis causes granulocyte-dominated chronic skin inflammation in miceSemantic proximity Read ↗

Disease-activated transcription factor: allergic reactions in human skin cause nuclear translocation of STAT-91 and induce synthesis of keratin K17.Semantic proximity Read ↗

Interleukin-1 and Cutaneous Inflammation: A Crucial Link Between Innate and Acquired ImmunitySemantic proximity Read ↗

Transcriptional response of bronchial epithelial cells to <i>Pseudomonas aeruginosa</i>: identification of early mediators of host defenseSemantic proximity Read ↗

Gene expression profile of cytokines and receptors of inflammation from cultured keratinocytes of burned patientsSemantic proximity Read ↗

Gene Expression Profile of Herpesvirus-Infected T Cells Obtained Using Immunomicroarrays: Induction of Proinflammatory MechanismsSemantic proximity Read ↗

Biologic activities of IL-1 and its role in human diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.