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Article

Regulation of human epidermal keratinocyte differentiation by the vitamin D receptor and its coactivators DRIP205, SRC2, and SRC3.

The Journal of investigative dermatology - 1 Apr 2007

Hawker Nathaniel P, Pennypacker Sally D, Chang Sandra M, Bikle Daniel D

Abstract excerpt

It has long been known that the active metabolite of vitamin D, 1,25 dihydroxyvitamin D(3), stimulates differentiation and inhibits proliferation in epidermal keratinocytes through interaction with the vitamin D receptor (VDR). VDR functions through the coordinate binding of vitamin D response elements in the DNA and specific coactivator proteins which help to initiate transcription. It was recently observed that...

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Source

Identifiers

PMID: 17082781
DOI: 10.1038/sj.jid.5700624

Genes

VDR
SRC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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