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Article

Characterization of the IL-6 Responsive Elements in the γ Fibrinogen Gene Promoter

1 Oct 1995

Abstract excerpt

Fibrinogen, a hepatically derived class II acute phase protein, is the product of three separate genes, (A alpha, B beta, and gamma). The fibrinogen genes are expressed constitutively; however, their transcription can be significantly up-regulated by interleukin-6 (IL-6) and glucocorticoid. Inspection of the promoter region of the fibrinogen gamma gene revealed three hexanucleotide clusters of CTGGGA that are...

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PMID: 7592638
DOI: 10.1074/jbc.270.41.24287

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Source receipt: pubmed, retrieved 7 Sept 2026.

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