Article
Transcriptional Regulation of Complement Genes
1 Apr 1995
Abstract excerpt
Complement is a major effector system of host defense against invading pathogens. The recently completed cloning and structural characterization of almost all complement genes has allowed investigation of their regulation at the molecular level. Transcription of most complement genes is accelerated during the acute-phase response that follows tissue injury. Mechanisms regulating transcription of other acute-phase...
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