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Article

STAT3 Participates in Transcriptional Activation of the C-reactive Protein Gene by Interleukin-6

1 Apr 1996

Abstract excerpt

Interleukin-6 (IL-6) is the major cytokine inducing transcription of human C-reactive protein (CRP) during the acute phase response. STAT (signal transducers and activators of transcription) family members, recently shown to be important mediators of the effects of many cytokines including IL-6, generally induce their effects by binding to palindromic sequences with TT(N)5AA motifs. We report an IL-6 responsive...

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PMID: 8621622
DOI: 10.1074/jbc.271.16.9503

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STAT3 Participates in Transcriptional Activation of the C-reactive Protein Gene by Interleukin-6PMID 8621622Read ↗

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