Article
Chemical cross-linking of activated coagulation factor VII with soluble tissue factor: calcium ions are not essential for full amidolytic activity of the factor VIIa-tissue factor complex after complex formation.
Journal of biochemistry - 1 Apr 1995
Miyata T, Funatsu A, Kato H
Abstract excerpt
In the previous study involving a yeast expression system, a high molecular mass extracellular domain of human tissue factor (denoted as sTF alpha) with a high content of mannose residues was produced in abundance and 37 kDa sTF beta was obtained in a low yield [Shigematsu et al. (1992) J. Biol....
Topics
- Amides
- Amino Acid Sequence
- Blood Coagulation
- Calcium
- Cross-Linking Reagents
- Factor VIIa
- Factor Xa
- Kinetics
- Molecular Sequence Data
- Mutation
- Saccharomyces cerevisiae
- Solubility
- Thromboplastin