Article
One pathway can incorporate either adenine or dimethylbenzimidazole as an alpha-axial ligand of B12 cofactors in Salmonella enterica.
Journal of bacteriology - 1 Feb 2008
Anderson Peter J, Lango Jozsef, Carkeet Colleen, Britten Audrey, Kräutler Bernhard, Hammock Bruce D, Roth John R
Abstract excerpt
Corrinoid (vitamin B12-like) cofactors contain various alpha-axial ligands, including 5,6-dimethylbenzimidazole (DMB) or adenine. The bacterium Salmonella enterica produces the corrin ring only under anaerobic conditions, but it can form "complete" corrinoids aerobically by importing an "incomplete" corrinoid, such as cobinamide (Cbi), and adding appropriate alpha- and beta-axial ligands. Under aerobic...
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