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Article

The complexity of the BAFF TNF-family members: implications for autoimmunity.

Journal of autoimmunity - 1 Sept 2012

Lahiri Ayan, Pochard Pierre, Le Pottier Laëtitia, Tobón Gabriel J, Bendaoud Boutahar, Youinou Pierre, Pers Jacques-Olivier

Abstract excerpt

The B-cell activating factor belonging to the tumor-necrosis factor family BAFF contributes to autoimmune disorders. As such, BAFF might become a therapeutic target. However, this molecule has pleiotropic effects that are as numerous as they are varied. The real effect of each form (spliced, glycosylated, membrane bound, soluble, homotrimerized, heterotrimerized, multimerized) has not been well characterized yet....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22749832
DOI: 10.1016/j.jaut.2012.05.009

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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