Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Early diversification of the TNF superfamily in teleosts: genomic characterization and expression analysis.

Journal of immunology (Baltimore, Md. : 1950) - 15 Jun 2007

Glenney Gavin W, Wiens Gregory D

Abstract excerpt

The TNF superfamily (TNFSF) of proteins are cytokines involved in diverse immunological and developmental pathways. Little is known about their evolution or expression in lower vertebrate species. Bioinformatic searches of Zebrafish, Tetraodon, and Fugu genome and other teleost expressed sequence tag databases identified 44 novel gene sequences containing a TNF homology domain. This work reveals the following: 1)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Computational Biology
Share to Fishes
Share to Genomics

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Protein Structure, Secondary

Share to Receptors, Tumor Necrosis Factor

Share to Sequence Analysis, Protein

Share to TNF-Related Apoptosis-Inducing Ligand

Share to Tumor Necrosis Factors

Source

Identifiers

PMID: 17548633
DOI: 10.4049/jimmunol.178.12.7955

Genes

TNF
EDA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Early diversification of the TNF superfamily in teleosts: genomic characterization and expression analysis.PMID 17548633Read ↗

Regulation of tumor necrosis superfamily molecules, BAFF and APRIL, in response to pathogenic exposure and ligand stimulation in freshwater carp, Catla catlaSemantic proximity Read ↗

Characterization of the molecular structure, expression and bioactivity of the TNFSF13B (BAFF) gene of the South African clawed frog, Xenopus laevis.Semantic proximity Read ↗

Evolution of the inflammatory response in vertebrates: fish TNF-alpha is a powerful activator of endothelial cells but hardly activates phagocytes.Semantic proximity Read ↗

Historical perspectives on tumor necrosis factor and its superfamily: 25 years later, a golden journeySemantic proximity Read ↗

TWEAK, a New Secreted Ligand in the Tumor Necrosis Factor Family That Weakly Induces ApoptosisSemantic proximity Read ↗

The intriguing biology of the tumour necrosis factor/tumour necrosis factor receptor superfamily: players, rules and the gamesSemantic proximity Read ↗

The TNF receptor super family in immune regulationSemantic proximity Read ↗

An evolutionary and functional approach to the TNF receptor/ligand family.Semantic proximity Read ↗

Unraveling function in the TNF ligand and receptor families.Semantic proximity Read ↗

Tumor necrosis factor superfamily ligand mRNA expression profiles differ between humans and mice during homeostasis and between various murine kidney injuriesSemantic proximity Read ↗

A Novel TNF Receptor Family Member Binds TWEAK and Is Implicated in AngiogenesisSemantic proximity Read ↗

Structural and biological features of the TNF receptor and TNF ligand superfamilies: Interactive signals in the pathobiology of Hodgkin's diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.