The effects of differential polyadenylation on expression of the dihydrofolate reductase-encoding gene in Chinese hamster lung cells.

doi:10.1016/0378-1119(95)00381-f

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Article

The effects of differential polyadenylation on expression of the dihydrofolate reductase-encoding gene in Chinese hamster lung cells.

Gene - 3 Oct 1995

Yang H, Hussain A, Melera P W

Abstract excerpt

Three differently sized mRNAs are expressed from each of two DHFR (encoding dihydrofolate reductase) alleles present in the Chinese hamster lung (CHL) cell line, DC-3F. The relative abundancy of the transcripts produced from each allele differs dramatically as a result of differential utilization...

Topics

Alleles
Animals
Base Sequence
Cell Line
Cricetinae
Cricetulus
Gene Expression Regulation, Enzymologic
Lung
Molecular Sequence Data
Poly A
RNA, Messenger
Recombinant Fusion Proteins
Tetrahydrofolate Dehydrogenase

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