Article
High level accumulation of an aberrantly spliced human DHFR RNA species.
Molecules and cells - 30 Apr 1998
Lee S W, Gilboa E
Abstract excerpt
Cells transduced with either of two human DHFR minigenes express an RNA product which is considerably shorter than what would be predicted from the size of an unspliced transcript expressed from its DNA template. RNA blotting analysis has shown that this short transcript accumulated to exceedingl...
Topics
- 3T3 Cells
- Animals
- Base Sequence
- Cell Line
- DNA, Complementary
- Gene Expression
- Gene Expression Regulation, Enzymologic
- Genetic Vectors
- Humans
- Mice
- Molecular Sequence Data
- Mutation
- RNA
- RNA Splicing
- RNA, Messenger
- Recombinant Proteins
- Retroviridae
- Sequence Analysis, DNA