Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Low‐dose UVB radiation perturbs the functional expression of B7.1 and B7.2 co‐stimulatory molecules on human Langerhans cells

1 Oct 1995

Abstract excerpt

In previous studies, we have shown that ultraviolet (UV) B radiation perturbs the APC function of Langerhans cells (LC) by interfering with as-yet unidentified co-stimulatory signals. Recently, B7.1 and B7.2 on APC were shown to deliver important co-stimulatory signals through interaction with their counter receptors CD28 and CTLA-4 on T cells. To determine whether UVB affects the functional expression of B7.1 or...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Immunotherapy and Biomarkers
Share to Immunotherapy and Immune Responses
Share to T-cell and B-cell Immunology

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 7589083
DOI: 10.1002/eji.1830251022

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Low‐dose UVB radiation perturbs the functional expression of B7.1 and B7.2 co‐stimulatory molecules on human Langerhans cellsPMID 7589083Read ↗

UVA radiation impairs phenotypic and functional maturation of human dermal dendritic cells.Semantic proximity Read ↗

Ultraviolet B radiation suppresses endocytosis, subsequent maturation, and migration activity of langerhans cell-like dendritic cells.Semantic proximity Read ↗

UV Radiation Induces the Epidermal Recruitment of Dendritic Cells that Compensate for the Depletion of Langerhans Cells in Human Skin.Semantic proximity Read ↗

Role of excision repair in UVB-induced depletion and recovery of human epidermal Langerhans cells.Semantic proximity Read ↗

Dynamic nature and function of epidermal Langerhans cells in vivo and in vitro: a review, with emphasis on human Langerhans cells.Semantic proximity Read ↗

Epidermal and dermal dendritic cells display differential activation and migratory behavior while sharing the ability to stimulate CD4+ T cell proliferation in vivo.Semantic proximity Read ↗

Granulocyte macrophage--colony-stimulating factor (GM-CSF) decreases CD1a expression by human Langerhans cells and increases proliferation in the mixed epidermal cell-lymphocyte reaction (MELR).Semantic proximity Read ↗

Suppressive and enhancing effects of ultraviolet B radiation on expression of contact hypersensitivity in man.Semantic proximity Read ↗

Langerhans' cells in vernal keratoconjunctivitis express the costimulatory molecule B7-2 (CD86), but not B7-1 (CD80).Semantic proximity Read ↗

Ultraviolet B suppresses immunity by inhibiting effector and memory T cells.Semantic proximity Read ↗

Migration and maturation of Langerhans cells in skin transplants and explants.Semantic proximity Read ↗

Splenic contribution to the recovery of ATPase/Ia+ epidermal cells in the skin of mice after exposure to ultraviolet radiation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.