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Article

UV Radiation Induces the Epidermal Recruitment of Dendritic Cells that Compensate for the Depletion of Langerhans Cells in Human Skin.

The Journal of investigative dermatology - 1 Aug 2015

Achachi Amine, Vocanson Marc, Bastien Philippe, Péguet-Navarro Josette, Grande Sophie, Goujon Catherine, Breton Lionel, Castiel-Higounenc Isabelle, Nicolas Jean-François, Gueniche Audrey

Abstract excerpt

UVR causes skin injury and inflammation, resulting in impaired immune function and increased skin cancer risk. Langerhans cells (LCs), the immune sentinels of the epidermis, are depleted for several days following a single UVR exposure and can be reconstituted from circulating monocytes. However, the differentiation pathways leading to the recovery of a normal pool of LCs is still unclear. To study the dynamic...

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PMID: 25806853
DOI: 10.1038/jid.2015.118

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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