Article
Dynamic nature and function of epidermal Langerhans cells in vivo and in vitro: a review, with emphasis on human Langerhans cells.
The Histochemical journal - 1 Oct 1992
Teunissen M B
Abstract excerpt
Epidermal Langerhans cells (LC) are Birbeck granule-containing bone-marrow-derived cells, which are located mainly in the suprabasal layer of the epidermis. They can be readily identified by their strong expression of CD1a and MHC class II molecules. In addition to these 'classical' properties, an extensive phenotypic profile of normal human LC, summarized in this review, is now available. The powerful capacity...
Topics
- Animals
- Antigens, CD
- Cells, Cultured
- Dermatitis, Contact
- Epidermal Cells
- Epidermis
- Histocompatibility Antigens Class I
- Histocompatibility Antigens Class II
- Humans
- Langerhans Cells
- Microscopy, Electron
