Article
Comparison of the sites of reaction of three polycyclic aromatic hydrocarbons in the supF gene.
Mutation research - 1 Apr 1994
Ross H L, Lee H, Harvey R G, Dipple A
Abstract excerpt
The distribution of hydrocarbon-DNA adducts through the supF gene in plasmid pS189 was examined using the polymerase arrest assay. For three hydrocarbon dihydrodiol epoxides, derived from 5-methylchrysene, 7-methylbenz[a]anthracene, and benzo[a]pyrene, that exhibit a preference for reaction with...
Topics
- Base Sequence
- Benz(a)Anthracenes
- Benzo(a)pyrene
- Carcinogens
- Chrysenes
- DNA
- DNA Adducts
- Epoxy Compounds
- Molecular Sequence Data
- Mutation
- Structure-Activity Relationship