Article
The erythromycin resistance gene of the Corynebacterium xerosis R-plasmid pTP10 also carrying chloramphenicol, kanamycin, and tetracycline resistances is capable of transposition in Corynebacterium glutamicum.
Plasmid - 1 May 1995
Tauch A, Kassing F, Kalinowski J, Pühler A
Abstract excerpt
The clinical isolate Corynebacterium xerosis M82B carries the 50-kb R-plasmid pTP10 that confers resistance to the antibiotics chloramphenicol, kanamycin, erythromycin, and tetracycline. A detailed restriction map of pTP10 was constructed by cloning and analyzing restriction fragments of pTP10 in Escherichia coli. The resistance determinants of pTP10 were located by studying the phenotype of the recombinant...
Topics
- Blotting, Southern
- Chloramphenicol Resistance
- Cloning, Molecular
- Corynebacterium
- DNA Transposable Elements
- Drug Resistance, Microbial
- Erythromycin
- Escherichia coli
- Genetic Vectors
- Kanamycin Resistance
