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Article

Bacteriophage-based vectors for site-specific insertion of DNA in the chromosome of Corynebacteria.

Gene - 15 Apr 2007

Oram Mark, Woolston Joelle E, Jacobson Andrew D, Holmes Randall K, Oram Diana M

Abstract excerpt

In Corynebacterium diphtheriae, diphtheria toxin is encoded by the tox gene of some temperate corynephages such as beta. beta-like corynephages are capable of inserting into the C. diphtheriae chromosome at two specific sites, attB1 and attB2. Transcription of the phage-encoded tox gene, and many chromosomally encoded genes, is regulated by the DtxR protein in response to Fe(2+) levels. Characterizing...

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Identifiers

PMID: 17275217
DOI: 10.1016/j.gene.2006.12.003
PMCID: PMC1913493

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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