Article
Alternative thymidylate synthase, ThyX, involved in Corynebacterium glutamicum ATCC 13032 survival during stationary growth phase.
FEMS microbiology letters - 1 Jun 2010
Park Mijeong, Cho Sukhyeong, Lee Hosa, Sibley Carol Hopkins, Rhie Hogun
Abstract excerpt
A BLASTP search has shown the presence of a gene homologous to an alternative thymidylate synthase (TS), thyX, in Corynebacterium glutamicum ATCC 13032. To determine if thyX is functionally analogous to thyA, thyX was cloned in a plasmid and the resulting construct was transferred by transformation into a thyA mutant of Escherichia coli. The ThyX from C. glutamicum compensated for the defect in TS-deficient E....
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