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Article

SCS1, a multicopy suppressor of hsp60-ts mutant alleles, does not encode a mitochondrially targeted protein.

Molecular and cellular biology - 1 Oct 1995

Shu Y, Hallberg R L

Abstract excerpt

We identified and isolated a Saccharomyces cerevisiae gene which, when overexpressed, suppressed the temperature-sensitive phenotype of cells expressing a mutant allele of the gene encoding the mitochondrial chaperonin, Hsp60. This gene, SCS1 (suppressor of chaperonin sixty-1), encodes a 757-amino-acid protein of as yet unknown function which, nonetheless, has human, rice, and Caenorhabditis elegans homologs with...

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PMID: 7565713
DOI: 10.1128/MCB.15.10.5618
PMCID: PMC230812

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