SCS1, a multicopy suppressor of hsp60-ts mutant alleles, does not encode a mitochondrially targeted protein.

doi:10.1128/MCB.15.10.5618

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Article

SCS1, a multicopy suppressor of hsp60-ts mutant alleles, does not encode a mitochondrially targeted protein.

Molecular and cellular biology - 1 Oct 1995

Shu Y, Hallberg R L

Abstract excerpt

We identified and isolated a Saccharomyces cerevisiae gene which, when overexpressed, suppressed the temperature-sensitive phenotype of cells expressing a mutant allele of the gene encoding the mitochondrial chaperonin, Hsp60. This gene, SCS1 (suppressor of chaperonin sixty-1), encodes a 757-amin...

Topics

Alleles
Amino Acid Sequence
Base Sequence
Basic Helix-Loop-Helix Transcription Factors
Chaperonin 60
Cloning, Molecular
Cytosol
Fungal Proteins
Gene Dosage
Gene Expression Regulation, Fungal
Genes, Fungal
Genes, Suppressor
Mitochondria
Molecular Sequence Data
RNA, Messenger
Recombinant Fusion Proteins
Repressor Proteins
Saccharomyces cerevisiae Proteins

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Identifiers

PMID: 7565713
DOI: 10.1128/MCB.15.10.5618
PMCID: PMC230812

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7565713-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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