Article
Cloning and mutagenesis of a serotype-specific DNA region involved in encapsulation and virulence of Actinobacillus pleuropneumoniae serotype 5a: concomitant expression of serotype 5a and 1 capsular polysaccharides in recombinant A. pleuropneumoniae serotype 1.
Infection and immunity - 1 Jul 1998
Ward C K, Lawrence M L, Veit H P, Inzana T J
Abstract excerpt
A DNA region involved in Actinobacillus pleuropneumoniae serotype 5 capsular polysaccharide (CP) biosynthesis was identified and characterized by using a probe specific for the cpxD gene involved in CP export. The adjacent serotype 5-specific CP biosynthesis region was cloned from a 5.8-kb BamHI...
Topics
- Actinobacillus pleuropneumoniae
- Alleles
- Amino Acid Sequence
- Animals
- Bacterial Capsules
- Base Sequence
- Cloning, Molecular
- DNA, Bacterial
- Mice
- Molecular Sequence Data
- Mutagenesis
- Polysaccharides, Bacterial
- Serotyping