Article
Population differences in the frequency of the factor V Leiden variant among people with clinically symptomatic protein C deficiency.
Journal of medical genetics - 1 Jul 1995
Hallam P J, Millar D S, Krawczak M, Kakkar V V, Cooper D N
Abstract excerpt
The factor V Leiden variant, responsible for the phenomenon of activated protein C resistance, was found to be less frequent among British (0.06) and Swedish/Danish (0.15) protein C deficiency patients than previously reported in a Dutch study (0.19). In the Swedish population, a significantly in...
Topics
- Alleles
- Enzyme Activation
- Ethnicity
- Factor V
- Factor V Deficiency
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Germany
- Humans
- Male
- Protein C Deficiency
- Scandinavian and Nordic Countries
- Thrombosis
- United Kingdom