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Article

Population differences in the frequency of the factor V Leiden variant among people with clinically symptomatic protein C deficiency.

Journal of medical genetics - 1 Jul 1995

Hallam P J, Millar D S, Krawczak M, Kakkar V V, Cooper D N

Abstract excerpt

The factor V Leiden variant, responsible for the phenomenon of activated protein C resistance, was found to be less frequent among British (0.06) and Swedish/Danish (0.15) protein C deficiency patients than previously reported in a Dutch study (0.19). In the Swedish population, a significantly increased frequency of the factor V Leiden allele was apparent in protein C deficiency patients as compared to healthy...

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Identifiers

PMID: 7562967
DOI: 10.1136/jmg.32.7.543
PMCID: PMC1050547

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Population differences in the frequency of the factor V Leiden variant among people with clinically symptomatic protein C deficiency.PMID 7562967Read ↗

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Prevalence of protein C deficiency in the healthy population.Semantic proximity Read ↗

Six different point mutations in seven Danish families with symptomatic protein C deficiency.Semantic proximity Read ↗

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Compound heterozygosity in a family with protein C deficiency illustrating the complexity of the underlying molecular mechanism.Semantic proximity Read ↗

Factor V Leiden: an additional risk factor for thrombosis in protein S deficient families?Semantic proximity Read ↗

The factor V R2 allele: risk of venous thromboembolism, factor V levels and resistance to activated protein C.Semantic proximity Read ↗

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