Article
Regions of beta 2 and beta 4 responsible for differences between the steady state dose-response relationships of the alpha 3 beta 2 and alpha 3 beta 4 neuronal nicotinic receptors.
The Journal of general physiology - 1 Jun 1995
Cohen B N, Figl A, Quick M W, Labarca C, Davidson N, Lester H A
Abstract excerpt
We constructed chimeras of the rat beta 2 and beta 4 neuronal nicotinic subunits to locate the regions that contribute to differences between the acetylcholine (ACh) dose-response relationships of the alpha 3 beta 2 and alpha 3 beta 4 receptors. Expressed in Xenopus oocytes, the alpha 3 beta 2 re...
Topics
- Acetylcholine
- Amino Acid Sequence
- Animals
- Dose-Response Relationship, Drug
- Electrophysiology
- Kinetics
- Molecular Sequence Data
- Mutation
- Neurons
- Nicotinic Agonists
- Oocytes
- Rats
- Receptors, Nicotinic
- Recombinant Fusion Proteins
- Xenopus