Article
Evidence for normal vitamin D receptor messenger ribonucleic acid and genotype in absorptive hypercalciuria.
The Journal of clinical endocrinology and metabolism - 1 Oct 1995
Zerwekh J E, Hughes M R, Reed B Y, Breslau N A, Heller H J, Lemke M, Nasonkin I, Pak C Y
Abstract excerpt
Absorptive hypercalciuria (a stone-forming condition) is characterized by gut hyperabsorption of calcium, hypercalciuria, and reduced bone density. Inasmuch as these features implicate enhanced calcitriol action in gut and bone, we analyzed the vitamin D receptor (VDR) gene to ascertain whether an abnormality of this gene marks patients with intestinal hyperabsorption of calcium. We have compared the frequency of...
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