Polymorphisms in the vitamin D receptor gene and the risk of calcium nephrolithiasis in children.

doi:10.1016/s0302-2838(03)00206-9

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Article

Polymorphisms in the vitamin D receptor gene and the risk of calcium nephrolithiasis in children.

European urology - 1 Jul 2003

Ozkaya Ozan, Söylemezoğlu Oğuz, Misirlioğlu Müge, Gönen Sevim, Buyan Necla, Hasanoğlu Enver

Abstract excerpt

OBJECTIVE: Polymorphism in the Vitamin D Receptor (VDR) gene has recently been reported to be associated with calcium metabolism disorders. This study was conducted to investigate the association of VDR gene polymorphism with the risk of calcium nephrolithiasis. METHODS: We investigated the VDR ApaI, BsmI and TaqI polymorphisms, in relation to serum calcium, phosphate, intact parathyroid hormone and...

Topics

Adolescent
Age Distribution
Calcium Phosphates
Case-Control Studies
Child
Child, Preschool
Cohort Studies
Confidence Intervals
Female
Genetic Markers
Genetic Predisposition to Disease
Humans
Incidence
Kidney Calculi

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Male

Polymerase Chain Reaction

Polymorphism, Genetic

Probability

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Open in PubMed

Identifiers

PMID: 12814692
DOI: 10.1016/s0302-2838(03)00206-9

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