Article
Effect of vitamin D receptor genotypes on calcium absorption, duodenal vitamin D receptor concentration, and serum 1,25 dihydroxyvitamin D levels in normal women.
Calcified tissue international - 1 Jun 1997
Kinyamu H K, Gallagher J C, Knezetic J A, DeLuca H F, Prahl J M, Lanspa S J
Abstract excerpt
It is well established that bone mineral density is under strong genetic control. Recently it was reported that the Bsm I restriction fragment length polymorphism of the vitamin D receptor (VDR) gene could account for up to 75% of the genetic variance in bone mineral density. However, the physiological basis for such an effect has not been established. The VDR gene codes for the vitamin D receptor protein which...
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