Article
Allelic frequency of p53 gene codon 72 polymorphism in urologic cancers.
Japanese journal of cancer research : Gann - 1 Aug 1995
Wu W J, Kakehi Y, Habuchi T, Kinoshita H, Ogawa O, Terachi T, Huang C H, Chiang C P, Yoshida O
Abstract excerpt
Alterations in the p53 tumor suppressor gene appear to be important in the development of many human tumors. The wild-type p53 gene has a polymorphism at codon 72 that presents the arginine (CGC) or proline (CCC) genotype, which recently has been reported to be associated with genetically determined susceptibility to smoking-related lung cancers. To determine whether this p53 genotype influences individual risk...
Topics
- Adult
- Aged
- Aged, 80 and over
- Alleles
- Base Sequence
- Carcinoma, Renal Cell
- Codon
- Female
- Genes, p53
- Genotype
- Humans
- Kidney Neoplasms
