Article
p53 Codon 72 polymorphism and urothelial cancer risk.
Cancer letters - 10 Jan 2003
Kuroda Yoshiki, Tsukino Hiromasa, Nakao Hiroyuki, Imai Hirohisa, Katoh Takahiko
Abstract excerpt
The p53 tumor suppressor gene is often mutated in various human cancers. Recently, the p53 codon 72 polymorphism has been extensively studied to determine the risk factors responsible for cancer formation. We investigated the genotype distribution of the p53 codon 72 polymorphism in 112 male urothelial cancer cases and 175 male unrelated non-cancer controls. The allelic frequencies in Japanese non-cancer controls...
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