Article
Relative roles of mutation and recombination in generating allelic polymorphism at an MHC class II locus in Peromyscus maniculatus.
Genetical research - 1 Oct 2003
Richman Adam D, Herrera L Gerardo, Nash Deanna, Schierup Mikkel H
Abstract excerpt
The MHC class II loci encoding cell surface antigens exhibit extremely high allelic polymorphism. There is considerable uncertainty in the literature over the relative roles of recombination and de novo mutation in generating this diversity. We studied class II sequence diversity and allelic polymorphism in two populations of Peromyscus maniculatus, which are among the most widespread and abundant mammals of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.