Article
Fully and long-term xenogeneic hematopoietic chimeras created in poorly concordant rat-mouse combinations: expression of hereditary donor characteristics.
Experimental hematology - 1 Oct 1995
Spach C, Lucchiari N, Bureaud N, Motta R
Abstract excerpt
We created fully and stable xenogeneic hematopoietic chimeras in "poorly concordant" rat-mouse strain combinations defined by their high histocompatibility-antigen disparity and by the high titer of mouse-serum natural cytotoxic antibodies (NcAb) to rat donor bone marrow cells (BMC). Recipients were adult male (C57BL/6 x DBA/2)F1 (BDF1) mice, and donors of untreated BMC were adult male WAG strain rats. We tried...
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