Article
Fully and long-term xenogeneic hematopoietic chimeras created in poorly concordant rat-mouse combinations: expression of hereditary donor characteristics.
Experimental hematology - 1 Oct 1995
Spach C, Lucchiari N, Bureaud N, Motta R
Abstract excerpt
We created fully and stable xenogeneic hematopoietic chimeras in "poorly concordant" rat-mouse strain combinations defined by their high histocompatibility-antigen disparity and by the high titer of mouse-serum natural cytotoxic antibodies (NcAb) to rat donor bone marrow cells (BMC). Recipients w...
Topics
- Animals
- Antibody-Dependent Cell Cytotoxicity
- Chimera
- Cytotoxicity, Immunologic
- Hemagglutination Tests
- Hematopoietic Stem Cell Transplantation
- Hemoglobins
- Lymphocyte Culture Test, Mixed
- Male
- Mice
- Mice, Inbred C3H
- Mice, Inbred C57BL
- Mice, Inbred DBA
- Mice, Inbred Strains
- Phenotype
- Rats
- Rats, Inbred F344
- Rats, Inbred Strains