A recombination event in the closely linked plasminogen and apolipoprotein(a) gene loci.

doi:10.1111/j.1399-0004.1995.tb03966.x

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Article

A recombination event in the closely linked plasminogen and apolipoprotein(a) gene loci.

Clinical genetics - 1 Jun 1995

Magnaghi P, Agazzi A, Semino O, Ferrari M, Barbui T, D'Angelo A, Taramelli R

Abstract excerpt

Genetic studies as well as in situ hybridisation data have strongly demonstrated that the genes coding for apoprotein(a) and plasminogen are linked and localised to chromosome 6 at band 6q26-27. We describe in this report the presence of a recombination event in a region of approximately 50 kb of DNA separating the two genes. The recombination was found in an Italian family, in which a mutation affecting both...

Topics

Adult
Aged
Apolipoproteins A
Base Sequence
Chromosomes, Human, Pair 6
Female
Haplotypes
Humans
Male
Molecular Sequence Data
Multigene Family
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Pedigree

Phenotype

Plasminogen

Polymerase Chain Reaction

Polymorphism, Restriction Fragment Length

Recombination, Genetic

Source

Open in PubMed

Identifiers

PMID: 7554360
DOI: 10.1111/j.1399-0004.1995.tb03966.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7554360-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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