Article
Allelic dimorphism in the human tissue-type plasminogen activator (TPA) gene as a result of an Alu insertion/deletion event.
Human genetics - 1 Feb 1992
Ludwig M, Wohn K D, Schleuning W D, Olek K
Abstract excerpt
Polymerase chain reaction and direct sequencing were used to investigate an amplified DNA fragment containing the suspected polymorphic site of all known intragenic restriction fragment length polymorphisms (RFLPs) within the human tissue-type plasminogen activator (TPA) gene. Sequence data obtai...
Topics
- Alleles
- Base Sequence
- Chromosome Deletion
- DNA
- DNA Transposable Elements
- Ethnicity
- Female
- Gene Frequency
- Homozygote
- Humans
- Leukocytes
- Male
- Models, Genetic
