Article
Higher lung cancer risk for younger African-Americans with the Pro/Pro p53 genotype.
Carcinogenesis - 1 Sept 1995
Jin X, Wu X, Roth J A, Amos C I, King T M, Branch C, Honn S E, Spitz M R
Abstract excerpt
A restriction fragment length polymorphism in codon 72 of the p53 gene has been implicated in lung cancer risk, although the functional significance of the polymorphism has not been determined. This association was examined in 109 lung cancer cases (67 African-American and 42 Mexican-American) and 114 controls (74 African-American and 40 Mexican-American) identified from a molecular epidemiological study of lung...
Topics
- Aged
- Alleles
- Analysis of Variance
- Base Sequence
- Black People
- Case-Control Studies
- Female
- Genes, p53
- Genotype
- Humans
- Lung Neoplasms
- Male
