Article
Genetic polymorphism in p53 codon 72 and skin cancer in southwestern Taiwan.
Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering - 1 Jan 2003
Chen Yen-Ching, Xu Lilian, Guo Yu-Liang Leon, Su Huey-Jen Jenny, Hsueh Yu-Mei, Smith Thomas J, Ryan Louise M, Lee Meei-Shyuan, Chaor Sheau-Chiou, Lee Julia Yu-Yun, Christiani David C
Abstract excerpt
The Pro/Pro polymorphism of p53 codon 72 has been reported to be related to bladder and lung cancer, but its relationship with skin cancer is unclear. We assessed the hypothesis that there is a relationship between the p53 codon 72, Pro/Pro polymorphism, cumulative arsenic exposure, and the risk of skin cancer in a hospital-based case-control study in southwestern Taiwan. From 1996 to 1999, 93 newly-diagnosed...
Topics
- Adult
- Aged
- Case-Control Studies
- Codon
- Female
- Genes, p53
- Genetic Predisposition to Disease
- Genotype
- Humans
- Male
- Middle Aged
- Polymerase Chain Reaction
- Polymorphism, Genetic