Article
Cloning and expression of CD24 gene in human hepatocellular carcinoma: a potential early tumor marker gene correlates with p53 mutation and tumor differentiation.
Cancer research - 15 Oct 1995
Huang L R, Hsu H C
Abstract excerpt
To search for genes related to hepatocarcinogenesis, the differential display technique for eukaryotic mRNA was conducted. We have cloned a gene that encodes the CD24 protein from the cDNA library of human hepatocellular carcinoma (HCC). A single 2.1-kb mRNA was identified in HCC specimens and th...
Topics
- Amino Acid Sequence
- Antigens, CD
- Base Sequence
- Biomarkers, Tumor
- CD24 Antigen
- Carcinoma, Hepatocellular
- DNA Primers
- DNA, Complementary
- DNA, Neoplasm
- Gene Expression Regulation, Neoplastic
- Genes, Neoplasm
- Genes, p53
- Humans
- Liver
- Liver Neoplasms
- Membrane Glycoproteins
- Molecular Sequence Data
- Mutation