Article
A human parthenogenetic chimaera.
Nature genetics - 1 Oct 1995
Strain L, Warner J P, Johnston T, Bonthron D T
Abstract excerpt
In mice, parthenogenetic embryos die at the early postimplantation stage as a result of developmental requirements for paternally imprinted genes, particularly for formation of extraembryonic tissues. Chimaeric parthenogenetic<==>normal mice are viable, however, due to non-random differences in distribution of their two cell types. Species differences in imprinting patterns in embryo and extra-embryonic tissues...
Topics
- Animals
- Base Sequence
- Chimera
- DNA Primers
- DNA, Satellite
- Disorders of Sex Development
- Female
- Genetic Markers
- Genotype
- Humans
- In Situ Hybridization, Fluorescence
- Infant