Article
The locus-specific enhancer activity of the class I major histocompatibility complex interferon-responsive element is associated with a gamma-interferon (IFN)-inducible factor distinct from STAT1alpha, p48, and IFN regulatory factor-1.
The Journal of biological chemistry - 22 Nov 1996
Vallejo A N, Pease L R
Abstract excerpt
Recent analyses of the upstream regulatory regions of the class I major histocompatibility complex genes in higher primates provided a generalized structural basis for the differential expression of A- and B-locus gene products in response to specific physiological stimulus. Among the regulatory...
Topics
- Benzoquinones
- Cell Line
- Cycloheximide
- DNA-Binding Proteins
- Enhancer Elements, Genetic
- HeLa Cells
- Humans
- Interferon Regulatory Factor-1
- Interferon-gamma
- Lactams, Macrocyclic
- Major Histocompatibility Complex
- Mutation
- Phosphoproteins
- Quinones