Article
Primate FSH-receptor promoter nucleotide sequence heterogeneity affects FSH-receptor transcription.
Molecular and cellular endocrinology - 12 Apr 2010
Brune Maik, Adams Christian, Gromoll Jörg
Abstract excerpt
Follicle-stimulating hormone (FSH) is essential for primate reproduction and acts via the FSH-receptor (FSHR). Although the FSHR expression is highly cell-specific, knowledge of the FSHR promoter and its transcriptional regulation is very limited. We applied a comparative genomic approach of important primate lineages to characterize the FSHR core promoter region. The core promoter sequences of the human and...
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