Article
Developmental Gene Expression in Leishmania donovani: Differential Cloning and Analysis of an Amastigote-Stage- Specific Gene
1 May 1994
Abstract excerpt
Leishmania protozoans are the causative agents of leishmaniasis, a major parasitic disease in humans. During their life cycle, Leishmania protozoans exist as flagellated promastigotes in the sand fly vector and as nonmotile amastigotes in the mammalian hosts. The promastigote-to-amastigote transformation occurs in the phagolysosomal compartment of the macrophage cell and is a critical step for the establishment...
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