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Article

Macrophage and T-Cell Gene Expression in a Model of Early Infection with the Protozoan Leishmania chagasi

24 Jun 2008

Abstract excerpt

Visceral leishmaniasis is a potentially fatal infectious disease caused by the protozoan parasite Leishmania infantum/chagasi in the New World, or by L. donovani or L. infantum/chagasi in the Old World. Infection leads to a variety of outcomes ranging from asymptomatic infection to active disease, characterized by fevers, cachexia, hepatosplenomegaly and suppressed immune responses. We reasoned that events...

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PMID: 18575603
DOI: 10.1371/journal.pntd.0000252

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