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Article

Characterization of the A2–A2rel gene cluster in Leishmania donovani: involvement of A2 in visceralization during infection

1 Feb 2001

Abstract excerpt

The A2 gene family is present in Leishmania donovani, which causes fatal visceral leishmaniasis in human patients, but is not present in Leishmania major, which causes cutaneous leishmaniasis infections. The A2 genes in L. donovani are stage specific and are expressed at high levels in the amastigote stage in the mammalian host, but are not expressed in the promastigote stage in the insect sandfly vector. The A2...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 11251814
DOI: 10.1046/j.1365-2958.2001.02286.x

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