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Article

The Developmental Expression of A2 Amastigote-specific Genes Is Post-transcriptionally Mediated and Involves Elements Located in the 3′-Untranslated Region

1 Jul 1996

Abstract excerpt

Leishmania donovani is a protozoan parasite that exists as a free-living promastigote in the sandfly insect vector and as an amastigote inside the mammalian host macrophage phagolysosome compartment. The L. donovani A2 genes have been described previously as developmentally expressed in amastigotes but can be induced experimentally in promastigotes by a combination of pH and temperature shifts, conditions that...

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PMID: 8663340
DOI: 10.1074/jbc.271.29.17081

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