Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Comparative Expression Profiling of Leishmania: Modulation in Gene Expression between Species and in Different Host Genetic Backgrounds

6 Jul 2009

Abstract excerpt

BACKGROUND: Genome sequencing of Leishmania species that give rise to a range of disease phenotypes in the host has revealed highly conserved gene content and synteny across the genus. Only a small number of genes are differentially distributed between the three species sequenced to date, L. major, L. infantum and L. braziliensis. It is not yet known how many of these genes are expressed in the disease-promoting...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Parasites and Host Interactions
Share to Research on Leishmaniasis Studies
Share to Trypanosoma species research and implications

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19582145
DOI: 10.1371/journal.pntd.0000476

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Comparative Expression Profiling of Leishmania: Modulation in Gene Expression between Species and in Different Host Genetic BackgroundsPMID 19582145Read ↗

Genome-wide gene expression profiling analysis of Leishmania major and Leishmania infantum developmental stages reveals substantial differences between the two speciesSemantic proximity Read ↗

In vivo transcriptional analysis of mice infected with Leishmania major unveils cellular heterogeneity and altered transcriptomic profiling at single-cell resolutionSemantic proximity Read ↗

Differential Gene Expression and Infection Profiles of Cutaneous and Mucosal Leishmania braziliensis Isolates from the Same PatientSemantic proximity Read ↗

Leishmania: conserved evolution--diverse diseases.Semantic proximity Read ↗

Comparative genomics: from genotype to disease phenotype in the leishmaniases.Semantic proximity Read ↗

In vivo reprogramming of murine host immune response genes following Leishmania major infectionSemantic proximity Read ↗

Simultaneous transcriptional profiling of Leishmania major and its murine macrophage host cell reveals insights into host-pathogen interactionsSemantic proximity Read ↗

Tissue and host species-specific transcriptional changes in models of experimental visceral leishmaniasisSemantic proximity Read ↗

Changes in Macrophage Gene Expression Associated with Leishmania (Viannia) braziliensis InfectionSemantic proximity Read ↗

Transcriptional signatures in human macrophage-like cells infected by Leishmania infantum, Leishmania major and Leishmania tropicaSemantic proximity Read ↗

Tissue specific dual RNA-seq defines host-parasite interplay in murine visceral leishmaniasis caused by <i>Leishmania donovani</i> and <i>Leishmania infantum</i>Semantic proximity Read ↗

Advances in Understanding Leishmania Pathobiology: What Does RNA-Seq Tell Us?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.