Transcriptome analysis during the process of<i>in vitro</i>differentiation of<i>Leishmania donovani</i>using genomic microarrays

Abstract excerpt

Leishmania donovani causes visceral disease (kala-azar), a major health problem throughout the tropics with 500 000 new cases every year. Leishmania differentiates from the promastigote to the amastigote form to establish infection in a mammalian host. To understand the process of differentiation, we assessed the global variation in gene expression in promastigotes, an intermediate stage of differentiation (PA24)...

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