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Article

Elements Controlling the Expression and Induction of the Skin Hyperproliferation-associated Keratin K6

1 Sept 1995

Abstract excerpt

The suprabasal keratin 6 (K6) is remarkable among the keratins as, in addition to being constitutively expressed in different stratified epithelia, it is induced in epidermis under hyperproliferative conditions, such as benign or malignant tumors, psoriasis, and wound healing. In addition, this keratin is also induced in skin treated with 12-O-tetradecanoylphorbol-13-acetate or retinoic acid (RA). These...

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PMID: 7545670
DOI: 10.1074/jbc.270.36.21362

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