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Article

Identification of the retinoic acid and thyroid hormone receptor-responsive element in the human K14 keratin gene.

The Journal of investigative dermatology - 1 Dec 1992

Tomic-Canic M, Sunjevaric I, Freedberg I M, Blumenberg M

Abstract excerpt

The promoter of human K14 keratin gene, specific for the basal layer of stratified epithelia, is regulated by nuclear receptors for retinoic acid and thyroid hormone. However, the DNA sequences responsible for this regulation have not yet been identified. To identify the retinoic acid-responsive site, we have devised a simple site-specific mutagenesis method and introduced mutations into the K14 keratin gene...

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Source

Identifiers

PMID: 1281867
DOI: 10.1111/1523-1747.ep12614806

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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