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Article

Novel Mechanism of Steroid Action in Skin through Glucocorticoid Receptor Monomers

1 Jun 2000

Abstract excerpt

Glucocorticoids (GCs), important regulators of epidermal growth, differentiation, and homeostasis, are used extensively in the treatment of skin diseases. Using keratin gene expression as a paradigm of epidermal physiology and pathology, we have developed a model system to study the molecular mechanism of GCs action in skin. Here we describe a novel mechanism of suppression of transcription by the glucocorticoid...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 10825196
DOI: 10.1128/mcb.20.12.4328-4339.2000

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