Co-ordinated regulation of amino sugar biosynthesis and degradation: the NagC repressor acts as both an activator and a repressor for the transcription of the glmUS operon and requires two separated NagC binding sites.

Abstract excerpt

The NagC repressor controls the expression of the divergently transcribed nagE-nagBACD operons involved in the uptake and degradation of the amino sugars, N-acetyl-D-glucosamine (GlcNAc) and glucosamine (GlcN). The glmUS operon, encoding proteins necessary for the synthesis of GlcN (glmS) and the...

Topics

• Acetylglucosamine
• Amino Sugars
• Bacterial Proteins
• Base Sequence
• DNA, Bacterial
• Enzyme Repression
• Escherichia coli Proteins
• Gene Expression Regulation, Bacterial
• Glucosamine
• Molecular Sequence Data
• Mutation
• Nucleotidyltransferases
• Operator Regions, Genetic
• Operon