Article
How to achieve constitutive expression of a gene within an inducible operon: the example of the nagC gene of Escherichia coli.
Journal of bacteriology - 1 May 1996
Plumbridge J
Abstract excerpt
The nagC gene, encoding the NagC repressor/activator of the nag regulon, is part of the nagBACD operon. When the promoter-proximal nagB and nagA genes are induced 20- to 40-fold, the nagC gene is induced only two- to threefold. In addition to being transcribed as part of the polycistronic nagBACD mRNA, nagC is also expressed from two promoters located within the upstream nagA gene. These promoters are comparable...
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